Like with sight and eyeballs, Hand Sourced Abilities don't require the user to physically have a dexterous humanoid hand with recognizable fingers. Some creatures with claws, tentacles, or other appendages can use Hand Abilities without problem. However, something of this nature is always required. If a creature that typically has literal hands has their arms Hacked or has their hands cut off, then they are unable to use Hand Sourced Abilities. It may be possible for them to find other ways to use these abilities in the future, but that's up to GM discretion.
The Range of Hand Sourced Abilities is the reach of the User's arm (or other appendage). This depends in part on the creature's size, but is usually 5 feet.